Establishment of tree shrew chronic morphine dependent model
نویسندگان
چکیده
منابع مشابه
[Establishment of tree shrew chronic morphine dependent model].
The clinical use of morphine to reduce pain is limited because of its drug tolerance, dependence and addiction. In the present study, the tree shrews (Tupaia belangeri chinensis) developed morphine tolerance and chronic morphine dependence by morphine injections with increasing doses (5, 10, 15, 20 mg/kg body weight for 7 days). Meanwhile, the naloxone (1.25 mg/kg body weight)-induced condition...
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ژورنال
عنوان ژورنال: Zoological Research
سال: 2013
ISSN: 0254-5853
DOI: 10.3724/sp.j.1141.2012.01014